Gadsby - Ernest Vincent Wright

Fifty-year-old John Gadsby is alarmed by the decline of his hometown, Branton Hills, and rallies the city's young people to form an "Organization of Youth" to build civic spirit and improve living standards. Gadsby and his youthful army, despite some opposition, transform Branton Hills from a stagnant municipality into a bustling, thriving city. The story begins around 1906 and continues through World War I, Prohibition, and President Warren G. Harding's administration.

"Gadsby" is a lipogram - a whole novel of some 50.000 words without a single instance of the letter E. When it first appeared in 1939 it was hardly noticed by the general public, but a modern reviewer called it "probably the most ambitious work ever attempted in this genre". Hardcopies of the book are extremely rare and sell for thousands of dollars. (Summary by Availle and Wikipedia)